Dysregulation of metabolic‐associated pathways in muscle of breast cancer patients: preclinical evaluation of interleukin‐15 targeting fatigue

• Main Authors: Joseph Bohlen (Author), Sarah L. McLaughlin (Author), Hannah Hazard‐Jenkins (Author), Aniello M. Infante (Author), Cortney Montgomery (Author), Mary Davis (Author), Emidio E. Pistilli (Author)
• Format: Book
• Published: Wiley, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Breast cancer patients report a perception of increased muscle fatigue, which can persist following surgery and standardized therapies. In a clinical experiment, we tested the hypothesis that pathways regulating skeletal muscle fatigue are down‐regulated in skeletal muscle of bre...