Icariin Enhances Bone Repair in Rabbits with Bone Infection during Post-infection Treatment and Prevents Inhibition of Osteoblasts by Vancomycin

• Main Authors: Yang Zhang (Author), Lifeng Shen (Author), Zhujun Mao (Author), Nani Wang (Author), Xuping Wang (Author), Xiaowen Huang (Author), Ying Hu (Author), Dan Shou (Author), Chengping Wen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Vancomycin is an effective antibiotic for treatment of bone infection caused by Staphylococcus aureus, however, a high local concentration of vancomycin might induce a delay in bone union. Icariin has been reported to suppress osteoclastogenes and promote osteogenesis. Our study aimed to investigate...