Improved Malaria Therapy with Cationic Nanocapsules Demonstrated in <i>Plasmodium berghei</i>-Infected Rodents Using Whole Blood Surrogate Population PK/PD Modeling

Improved Malaria Therapy with Cationic Nanocapsules Demonstrated in <i>Plasmodium berghei</i>-Infected Rodents Using Whole Blood Surrogate Population PK/PD Modeling

<b>Objectives</b>: Investigating how nanoparticle systems interact in whole blood (WB) is critical to evaluating the effectiveness of malaria therapy. Methods: We decided to establish a pharmacokinetic/pharmacodynamic (PK/PD) model of the quinine population in WB using <i>Plasmodiu...

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Main Authors: Tamara Ramos Maciel (Author), Ana Claudia Funguetto-Ribeiro (Author), Laura Ben Olivo (Author), Flávia Elizabete Guerra Teixeira (Author), Camila de Oliveira Pacheco (Author), Bibiana Verlindo de Araujo (Author), Sandra Elisa Haas (Author)
Format: Book
Published: MDPI AG, 2024-10-01T00:00:00Z.
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