Bioequivalence and the food effect of macitentan/tadalafil 10/20 fixed‐dose combination tablets versus the use of single‐component tablets in healthy subjects

• Asıl Yazarlar: Jennifer Lynn Ford (Yazar), Ahad Sabet (Yazar), Jaya Natarajan (Yazar), Hans Stieltjes (Yazar), Daniel L. Chao (Yazar), Navin Goyal (Yazar), Denes Csonka (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Wiley, 2024-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract The primary aim was to demonstrate bioequivalence between the 10/20 mg fixed‐dose combination (FDC) of macitentan/tadalafil in a single tablet and the free combination of both drugs, and to evaluate the food effect on the 10/20 mg FDC in healthy participants. In this single‐center, randomiz...