The functional role of p38 MAPK pathway in malignant brain tumors

• Main Authors: Nathália Grave (Author), Thamiris Becker Scheffel (Author), Fernanda Fernandes Cruz (Author), Liliana Rockenbach (Author), Márcia Inês Goettert (Author), Stefan Laufer (Author), Fernanda Bueno Morrone (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gliomas are extremely debilitating malignant brain tumors with very limited response to therapies. The initiation and progression of gliomas can be attributed to several molecular abnormalities, such as mutations in important regulatory networks. In this regard, the mitogen-activated protein kinases...