Inhibition of Ubiquitin-Specific Proteases as a Novel Anticancer Therapeutic Strategy

• Main Authors: Tao Yuan (Author), Fangjie Yan (Author), Meidan Ying (Author), Ji Cao (Author), Qiaojun He (Author), Hong Zhu (Author), Bo Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dysfunction or dysregulation of the ubiquitin proteasome system (UPS) is closely related to tumorigenesis and the development of multiple cancers. Targeting the UPS provides a new anticancer therapeutic strategy, but clinically available UPS-targeted inhibitors, including lenalidomide and bortezomib...