Hypoxic tumor-derived exosomal circular RNA SETDB1 promotes invasive growth and EMT via the miR-7/Sp1 axis in lung adenocarcinoma

• Hlavní autoři: Li Xu (Autor), Wei-Lin Liao (Autor), Qi-Jue Lu (Autor), Peng Zhang (Autor), Ji Zhu (Autor), Ge-Ning Jiang (Autor)
• Médium: Kniha
• Vydáno: Elsevier, 2021-03-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Hypoxia is a common feature of solid tumors and has been associated with tumor aggressiveness and poor prognosis. Exosomes are involved in mediating cellular-environment interactions. Circular RNAs (circRNAs) are a class of non-coding RNA broadly found in cells and exosomes. However, the functions a...