Case Report: Low Hematocrit Leading to Tacrolimus Toxicity
Tacrolimus is a calcineurin inhibitor characterized by a narrow therapeutic index and high intra- and inter-individual pharmacokinetic variability. Therapeutic drug monitoring in whole-blood is the standard monitoring procedure. However, tacrolimus extensively binds to erythrocytes, and tacrolimus w...
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Frontiers Media S.A.,
2021-08-01T00:00:00Z.
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