Case Report: Low Hematocrit Leading to Tacrolimus Toxicity

• প্রধান লেখক: Alexandre Piletta-Zanin (লেখক), Aurélie De Mul (লেখক), Nathalie Rock (লেখক), Pierre Lescuyer (লেখক), Caroline F. Samer (লেখক), Frédérique Rodieux (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Tacrolimus is a calcineurin inhibitor characterized by a narrow therapeutic index and high intra- and inter-individual pharmacokinetic variability. Therapeutic drug monitoring in whole-blood is the standard monitoring procedure. However, tacrolimus extensively binds to erythrocytes, and tacrolimus w...