Novel Thiazole-Fused [4,5-<i>g</i>] or [5,4-<i>g</i>]Quinazolin-8-ones and Their Quinazoline Analogues: Synthesis and Biological Evaluation

• Main Authors: Nathan Broudic (Author), Alexandra Pacheco-Benichou (Author), Cécile Corbière (Author), Blandine Baratte (Author), Thomas Robert (Author), Stéphane Bach (Author), Hélène Solhi (Author), Rémy Le Guével (Author), Corinne Fruit (Author), Thierry Besson (Author)
• Format: Book
• Published: MDPI AG, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<b>Background/Objectives:</b> In connection with previous work on V-shaped polycyclic thiazolo[5,4-<i>f</i>]quinazolin-9-one and [5,4-<i>f</i>]quinazoline derivatives that can modulate the activity of various kinases, the synthesis of straight thiazole-fused [4,5-...