High Manganese Content of Lipid NanoMn (LNM) by Microfluidic Technology for Enhancing Anti-Tumor Immunity

• Main Authors: Jiawei Sun (Author), Jingjing Gong (Author), Lidong Gong (Author), Chuanda Zhu (Author), Longhao Li-Yang (Author), Jingya Wang (Author), Yuanyuan Yang (Author), Shiming Zhang (Author), Silu Liu (Author), Ji-Jun Fu (Author), Pengcheng Xu (Author)
• Format: Book
• Published: MDPI AG, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Immunotherapy is a clinically effective method for treating tumors. Manganese can activate the cGAS-STING signaling pathway and induce an anti-tumor immune response. However, its efficacy is hindered by non-specific distribution and low uptake rates. In this study, we employed microfluidic technolog...