Human ES Cell Culture Conditions Fail to Preserve the Mouse Epiblast State

• Main Authors: A. S. Devika (Author), Anna Montebaur (Author), S. Saravanan (Author), Raghu Bhushan (Author), Frederic Koch (Author), Smita Sudheer (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mouse embryonic stem cells (mESCs) and mouse epiblast stem cells (mEpiSCs) are the pluripotent stem cells (PSCs), derived from the inner cell mass (ICM) of preimplantation embryos at embryonic day 3.5 (E3.5) and postimplantation embryos at E5.5-E7.5, respectively. Depending on their environment, PSC...