Gene deficiency or pharmacological inhibition of PDCD4-mediated FGR signaling protects against acute kidney injury

• Main Authors: Xu Jing (Author), Dandan Ren (Author), Fei Gao (Author), Ye Chen (Author), Xiao Wu (Author), Yue Han (Author), Qingsheng Han (Author), Liang Li (Author), Xiaojie Wang (Author), Wei Tang (Author), Yan Zhang (Author)
• Format: Book
• Published: Elsevier, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recent studies have shown that programmed cell death 4 (PDCD4) modulates distinct signal transduction pathways in different pathological conditions. Despite acute and chronic immune responses elicited by ischemia contributing to the functional deterioration of the kidney, the contributions and mecha...