Comparative evaluation of intranasally delivered quetiapine loaded mucoadhesive microemulsion and polymeric nanoparticles for brain targeting: pharmacokinetic and gamma scintigraphy studies

Abstract Background Treatment in neurological disorders like schizophrenia requires continuous presence of drug in the brain for a prolonged period of time to achieve an effective therapeutic response. Delivery of antipsychotic drug quetiapine in the form of conventional delivery systems suffers fro...

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Autors principals: Brijesh Shah (Autor), Dignesh Khunt (Autor), Manju Misra (Autor)
Format: Llibre
Publicat: SpringerOpen, 2021-01-01T00:00:00Z.
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