JAK-STAT1/3-induced expression of signal sequence-encoding proopiomelanocortin mRNA in lymphocytes reduces inflammatory pain in rats

• Autors principals: Busch-Dienstfertig Melanie (Autor), Labuz Dominika (Autor), Wolfram Theresa (Autor), Vogel Nicole N (Autor), Stein Christoph (Autor)
• Format: Llibre
• Publicat: SAGE Publishing, 2012-11-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Proopiomelanocortin (POMC)-derived beta-endorphin_1-31 from immune cells can inhibit inflammatory pain. Here we investigated cytokine signaling pathways regulating POMC gene expression and beta-endorphin product...