Development of genetic system to inactivate a Borrelia turicatae surface protein selectively produced within the salivary glands of the arthropod vector.

• Main Authors: Job E Lopez (Author), Hannah K Wilder (Author), Reid Hargrove (Author), Christopher P Brooks (Author), Karin E Peterson (Author), Paul A Beare (Author), Daniel E Sturdevant (Author), Vijayaraj Nagarajan (Author), Sandra J Raffel (Author), Tom G Schwan (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Borrelia turicatae, an agent of tick-borne relapsing fever, is an example of a pathogen that can adapt to disparate conditions found when colonizing the mammalian host and arthropod vector. However, little is known about the genetic factors necessary during the tick-mammalian infectious cycle, there...