Requirement of Histone Deacetylase 6 for Interleukin-6 Induced Epithelial-Mesenchymal Transition, Proliferation, and Migration of Peritoneal Mesothelial Cells

• Main Authors: Yingfeng Shi (Author), Min Tao (Author), Jun Ni (Author), Lunxian Tang (Author), Feng Liu (Author), Hui Chen (Author), Xiaoyan Ma (Author), Yan Hu (Author), Xun Zhou (Author), Andong Qiu (Author), Shougang Zhuang (Author), Na Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims: Influenced by microenvironment, human peritoneal mesothelial cells (HPMCs) acquired fibrotic phenotype, which was identified as the protagonist for peritoneal fibrosis. In this study, we examined the role of histone deacetylase 6 (HDAC6) for interleukin-6 (IL-6) induced epithelial-mesenchymal...