C. acnes qPCR-Based Antibiotics Resistance Assay (ACQUIRE) Reveals Widespread Macrolide Resistance in Acne Patients and Can Eliminate Macrolide Misuse in Acne Treatment

• Main Authors: Jingheng Zhang (Author), Fang Yu (Author), Keyun Fu (Author), Xinyu Ma (Author), Yi Han (Author), Chi Ching Ali (Author), Haonan Zhou (Author), Yantao Xu (Author), Tingyue Zhang (Author), Shuntong Kang (Author), Yiming Xu (Author), Zhuolin Li (Author), Jiaqi Shi (Author), Shuai Gao (Author), Yongyi Chen (Author), Liyu Chen (Author), Jianglin Zhang (Author), Feizhou Zhu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundMacrolides have been widely used to treat moderate-to-severe acne for more than 50 years. However, the prevalent antibiotic resistance of Propionibacterium acnes, along with the absence of clinically available resistance tests, has made macrolide misuse a frequent occurrence around the glo...