Increased CD4+/CD8+ double-positive T cells in chronic Chagasic patients.

• Main Authors: Nicolas A Giraldo (Author), Natalia I Bolaños (Author), Adriana Cuellar (Author), Fanny Guzman (Author), Ana Maria Uribe (Author), Astrid Bedoya (Author), Natalia Olaya (Author), Zulma M Cucunubá (Author), Nubia Roa (Author), Fernando Rosas (Author), Víctor Velasco (Author), Concepción J Puerta (Author), John M González (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: CD4+/CD8+ double positive (DP) T cells have been described in healthy individuals as well as in patients with autoimmune and chronic infectious diseases. In chronic viral infections, this cell subset has effector memory phenotype and displays antigen specificity. No previous studies of d...