Design of taste masked enteric orodispersible tablets of diclofenac sodium by applying fluid bed coating technology

• Main Authors: Hadyah Faleh Alotaibi (Author), Samar Elsamaligy (Author), Gamal M. Mahrous (Author), Mohsen A. Bayomi (Author), Hanaa Abdelmonem Mahmoud (Author)
• Format: Book
• Published: Elsevier, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diclofenac sodium (DS) a non-steroidal anti-inflammatory drug has a bitter taste and is a local stomach irritant. The aim of this study was to formulate taste masked DS orally dispersible tablets (ODTs) with targeted drug release in the intestine. Pellets of DS were designed using sugar sphere cores...