Chelerythrine Attenuates Renal Ischemia/Reperfusion-induced Myocardial Injury by Activating CSE/H2S via PKC/NF-κB Pathway in Diabetic Rats

• Main Authors: Bo Hu (Author), Guangtao Xu (Author), Yongxia Zheng (Author), Fei Tong (Author), Ping Qian (Author), Xiaoyan Pan (Author), Xinmei Zhou (Author), Ruilin Shen (Author)
• Format: Book
• Published: Karger Publishers, 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Chelerythrine (CHE), a benzophenanthridine alkaloid, is a potent, selective, and cell-permeable protein kinase C (PKC) inhibitor. The purpose of the present study was to evaluate the effect of CHE on myocardial recovery after renal ischemia/reperfusion (I/R)-induced myocardial injur...