Differentiation-inducing factor-3 inhibits intestinal tumor growth in vitro and in vivo

• Main Authors: Naoya Kubokura (Author), Fumi Takahashi-Yanaga (Author), Masaki Arioka (Author), Tatsuya Yoshihara (Author), Kazunobu Igawa (Author), Katsuhiko Tomooka (Author), Sachio Morimoto (Author), Yoshimichi Nakatsu (Author), Teruhisa Tsuzuki (Author), Yusaku Nakabeppu (Author), Takayuki Matsumoto (Author), Takanari Kitazono (Author), Toshiyuki Sasaguri (Author)
• Format: Book
• Published: Elsevier, 2015-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Differentiation-inducing factor-1 (DIF-1) produced by Dictyostelium discoideum strongly inhibits the proliferation of various types of cancer cells by suppression of the Wnt/β-catenin signal transduction pathway. In the present study, we examined the effect of differentiation-inducing factor-3 (DIF-...