Water T2 could predict functional decline in patients with dysferlinopathy

• Main Authors: Ursula Moore (Author), Ericky Caldas de Almeida Araújo (Author), Harmen Reyngoudt (Author), Heather Gordish‐Dressman (Author), Fiona E. Smith (Author), Ian Wilson (Author), Meredith James (Author), Anna Mayhew (Author), Laura Rufibach (Author), John W. Day (Author), Kristi J. Jones (Author), Diana X. Bharucha‐Goebel (Author), Emmanuelle Salort‐Campana (Author), Alan Pestronk (Author), Maggie C. Walter (Author), Carmen Paradas (Author), Tanya Stojkovic (Author), Madoka Mori‐Yoshimura (Author), Elena Bravver (Author), Elena Pegoraro (Author), Jerry R. Mendell (Author), The Jain COS Consortium (Author), Kate Bushby (Author), Andrew M. Blamire (Author), Volker Straub (Author), Pierre G. Carlier (Author), Jordi Diaz‐Manera (Author)
• Format: Book
• Published: Wiley, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Water T2 (T2H2O) mapping is increasingly being used in muscular dystrophies to assess active muscle damage. It has been suggested as a surrogate outcome measure for clinical trials. Here, we investigated the prognostic utility of T2H2O to identify changes in muscle function over...