Ronin overexpression induces cerebellar degeneration in a mouse model of ataxia

• Κύριοι συγγραφείς: Thomas P. Zwaka (Συγγραφέας), Marta Skowronska (Συγγραφέας), Ronald Richman (Συγγραφέας), Marion Dejosez (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: The Company of Biologists, 2021-06-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Spinocerebellar ataxias (SCAs) are a group of genetically heterogeneous inherited neurodegenerative disorders characterized by progressive ataxia and cerebellar degeneration. Here, we used a mouse model to test a possible connection between SCA and Ronin (Thap11), a polyglutamine-containing transcri...