Ronin overexpression induces cerebellar degeneration in a mouse model of ataxia

• Những tác giả chính: Thomas P. Zwaka (Tác giả), Marta Skowronska (Tác giả), Ronald Richman (Tác giả), Marion Dejosez (Tác giả)
• Định dạng: Sách
• Được phát hành: The Company of Biologists, 2021-06-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Spinocerebellar ataxias (SCAs) are a group of genetically heterogeneous inherited neurodegenerative disorders characterized by progressive ataxia and cerebellar degeneration. Here, we used a mouse model to test a possible connection between SCA and Ronin (Thap11), a polyglutamine-containing transcri...