Chronic memantine administration prevents ouabain-induced hyperactivity in mice via maintenance of Na+, K+-ATPase activity in the hippocampus

We have previously reported that mice received intracerebroventricular injection of ouabain, an inhibitor of Na+, K+-ATPase, exhibited hyperactivity via overactivation of glutamatergic neurons. Here we investigated the effects of memantine, a blocker of N-methyl-d-aspartate receptors, on ouabain-ind...

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Main Authors: Yuki Kurauchi (Author), Taishi Yamada (Author), Akinori Hisatsune (Author), Takahiro Seki (Author), Hiroshi Katsuki (Author)
Format: Book
Published: Elsevier, 2019-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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