Schistosoma mansoni alter transcription of immunomodulatory gene products following in vivo praziquantel exposure.

• Principais autores: Paul McCusker (Autor), Claudia M Rohr (Autor), John D Chan (Autor)
• Formato: Livro
• Publicado em: Public Library of Science (PLoS), 2021-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Control of the neglected tropical disease schistosomiasis relies almost entirely on praziquantel (PZQ) monotherapy. How PZQ clears parasite infections remains poorly understood. Many studies have examined the effects of PZQ on worms cultured in vitro, observing outcomes such as muscle contraction. H...