Schistosoma mansoni alter transcription of immunomodulatory gene products following in vivo praziquantel exposure.

• Asıl Yazarlar: Paul McCusker (Yazar), Claudia M Rohr (Yazar), John D Chan (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Public Library of Science (PLoS), 2021-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Control of the neglected tropical disease schistosomiasis relies almost entirely on praziquantel (PZQ) monotherapy. How PZQ clears parasite infections remains poorly understood. Many studies have examined the effects of PZQ on worms cultured in vitro, observing outcomes such as muscle contraction. H...