Expression of Genes Related to Germ Cell Lineage and Pluripotency in Single Cells and Colonies of Human Adult Germ Stem Cells

• Main Authors: Sabine Conrad (Author), Hossein Azizi (Author), Maryam Hatami (Author), Mikael Kubista (Author), Michael Bonin (Author), Jörg Hennenlotter (Author), Karl-Dietrich Sievert (Author), Thomas Skutella (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of this study was to elucidate the molecular status of single human adult germ stem cells (haGSCs) and haGSC colonies, which spontaneously developed from the CD49f MACS and matrix- (collagen−/laminin+ binding-) selected fraction of enriched spermatogonia. Single-cell transcriptional profilin...