Effect of the antirheumatic medication methotrexate (MTX) on biomechanical compressed human periodontal ligament fibroblasts (hPDLFs)

• المؤلفون الرئيسيون: Claudia Welte-Jzyk (مؤلف), Vera Plümer (مؤلف), Sven Schumann (مؤلف), Andrea Pautz (مؤلف), Christina Erbe (مؤلف)
• التنسيق: كتاب
• منشور في: BMC, 2024-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Background The aim of this study was to investigate the in vitro effect of the antirheumatic drug methotrexate (MTX) on biomechanically compressed human periodontal ligament fibroblasts (hPDLFs), focusing on the expression of interleukin 6 (IL-6), as its upregulation is relevant to orthodon...