Deregulated expression of HDAC9 in B cells promotes development of lymphoproliferative disease and lymphoma in mice

• Main Authors: Veronica S. Gil (Author), Govind Bhagat (Author), Louise Howell (Author), Jiyuan Zhang (Author), Chae H. Kim (Author), Sven Stengel (Author), Francisco Vega (Author), Arthur Zelent (Author), Kevin Petrie (Author)
• Format: Book
• Published: The Company of Biologists, 2016-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Histone deacetylase 9 (HDAC9) is expressed in B cells, and its overexpression has been observed in B-lymphoproliferative disorders, including B-cell non-Hodgkin lymphoma (B-NHL). We examined HDAC9 protein expression and copy number alterations in primary B-NHL samples, identifying high HDAC9 express...