Rhythm and ROS: Hepatic Chronotherapeutic Features of Grape Seed Proanthocyanidin Extract Treatment in Cafeteria Diet-Fed Rats

• Main Authors: Antonio J. Cortés-Espinar (Author), Néstor Ibarz-Blanch (Author), Jorge R. Soliz-Rueda (Author), Béatrice Bonafos (Author), Christine Feillet-Coudray (Author), François Casas (Author), Francisca Isabel Bravo (Author), Enrique Calvo (Author), Javier Ávila-Román (Author), Miquel Mulero (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Polyphenols play a key role in the modulation of circadian rhythms, while the cafeteria diet (CAF) is able to perturb the hepatic biological rhythm and induce important ROS production. Consequently, we aimed to elucidate whether grape seed proanthocyanidin extract (GSPE) administration recovers the...