ProGeo-neo: a customized proteogenomic workflow for neoantigen prediction and selection

• Главные авторы: Yuyu Li (Автор), Guangzhi Wang (Автор), Xiaoxiu Tan (Автор), Jian Ouyang (Автор), Menghuan Zhang (Автор), Xiaofeng Song (Автор), Qi Liu (Автор), Qibin Leng (Автор), Lanming Chen (Автор), Lu Xie (Автор)
• Формат: ‌
• Опубликовано: BMC, 2020-04-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Abstract Background Neoantigens can be differentially recognized by T cell receptor (TCR) as these sequences are derived from mutant proteins and are unique to the tumor. The discovery of neoantigens is the first key step for tumor-specific antigen (TSA) based immunotherapy. Based on high-throughput...