ProGeo-neo: a customized proteogenomic workflow for neoantigen prediction and selection

• Main Authors: Yuyu Li (Author), Guangzhi Wang (Author), Xiaoxiu Tan (Author), Jian Ouyang (Author), Menghuan Zhang (Author), Xiaofeng Song (Author), Qi Liu (Author), Qibin Leng (Author), Lanming Chen (Author), Lu Xie (Author)
• Format: Book
• Published: BMC, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Neoantigens can be differentially recognized by T cell receptor (TCR) as these sequences are derived from mutant proteins and are unique to the tumor. The discovery of neoantigens is the first key step for tumor-specific antigen (TSA) based immunotherapy. Based on high-throughput...