Tumor RNA-loaded nanoliposomes increases the anti-tumor immune response in colorectal cancer

• Main Authors: Dandong Dai (Author), You Yin (Author), Yuanbo Hu (Author), Ying Lu (Author), Hongbo Zou (Author), GuangZhao Lu (Author), Qianqian Wang (Author), Jie Lian (Author), Jie Gao (Author), Xian Shen (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose Tumor RNA vaccines can activate dendritic cells to generate systemic anti-tumor immune response. However, due to easily degraded of RNA, direct RNA vaccine is less effective. In this study, we optimized the method for preparing PEGylated liposom-polycationic DNA complex (LPD) nanoliposomes,...