Novel Sigma-2 receptor ligand A011 overcomes MDR in adriamycin-resistant human breast cancer cells by modulating ABCB1 and ABCG2 transporter function

• Asıl Yazarlar: Zhanwei Zeng (Yazar), Shiyi Liao (Yazar), Huan Zhou (Yazar), Hongyu Liu (Yazar), Jiantao Lin (Yazar), Yunsheng Huang (Yazar), Chenhui Zhou (Yazar), Daohua Xu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Multidrug resistance (MDR) is thought to be one of the main reasons for the failure of chemotherapy in cancers. ATP-binding cassette subfamily B member 1 (ABCB1) or P-glycoprotein (P-gp) and ATP-binding cassette subfamily G member 2 (ABCG2) play indispensable roles in cancer cell MDR. Sigma-2 (σ2) r...