Host-Based Biomarkers in Saliva for the Diagnosis of Pulmonary Tuberculosis in Children: A Mini-Review

• Principais autores: Nisreen Khambati (Autor), Laura Olbrich (Autor), Jerrold Ellner (Autor), Padmini Salgame (Autor), Rinn Song (Autor), Else Margreet Bijker (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The diagnosis of pulmonary tuberculosis (TB) in children remains a significant challenge due to its paucibacillary nature, non-specificity of symptoms and suboptimal sensitivity of available diagnostic methods. In young children particularly, it is difficult to obtain high-quality sputum specimens f...