Integrated dose-response metabolomics with therapeutic effects and adverse reactions may demystify the dosage of traditional Chinese medicine

• Main Authors: Yan-Yan Chen (Author), Jia-Qian Chen (Author), Yu-Ping Tang (Author), Er-Xin Shang (Author), Qi Zhao (Author), Jun-Bo Zou (Author), Ding-Qiao Xu (Author), Shi-Jun Yue (Author), Jie Yang (Author), Rui-Jia Fu (Author), Gui-Sheng Zhou (Author), Jin-Ao Duan (Author)
• Format: Book
• Published: BMC, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Traditional Chinese medicine (TCM) has been used to treat various diseases for thousands of years. However, the uncertainty of dosage as well as the lack of systemic evaluation of pharmacology and toxicology is one major reason why TCM remains mysterious and is not accepted world...