Predicting Blood Concentration of Tacrolimus in Patients With Autoimmune Diseases Using Machine Learning Techniques Based on Real-World Evidence

• Main Authors: Ping Zheng (Author), Ze Yu (Author), Liren Li (Author), Shiting Liu (Author), Yan Lou (Author), Xin Hao (Author), Peng Yu (Author), Ming Lei (Author), Qiaona Qi (Author), Zeyuan Wang (Author), Fei Gao (Author), Yuqing Zhang (Author), Yilei Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tacrolimus is a widely used immunosuppressive drug in patients with autoimmune diseases. It has a narrow therapeutic window, thus requiring therapeutic drug monitoring (TDM) to guide the clinical regimen. This study included 193 cases of tacrolimus TDM data in patients with autoimmune diseases at So...