Development of a Porcine Full-Thickness Burn Hypertrophic Scar Model and Investigation of the Effects of Shikonin on Hypertrophic Scar Remediation

• Main Authors: Xingwang Deng (Author), Qian Chen (Author), Lijuan Qiang (Author), Mingwei Chi (Author), Nan Xie (Author), Yinsheng Wu (Author), Ming Yao (Author), Dan Zhao (Author), Jiaxiang Ma (Author), Ning Zhang (Author), Yan Xie (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hypertrophic scars formed after burns remain a challenge in clinical practice. Development of effective scar therapies relies on validated animal models that mimic human hypertrophic scars. A consistent porcine full-thickness burn hypertrophic scar model has yet to be developed. We have previously r...