Chemotactic migration of newly excysted juvenile Clonorchis sinensis is suppressed by neuro-antagonists.

• Main Authors: Shunyu Li (Author), Jin-Ho Song (Author), Tae Im Kim (Author), Won Gi Yoo (Author), Moo-Ho Won (Author), Fuhong Dai (Author), Sung-Jong Hong (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The metacercariae of the Clonorchis sinensis liver fluke excyst in the duodenum of mammalian hosts, and the newly excysted juveniles (CsNEJs) migrate along the bile duct via bile chemotaxis. Cholic acid is a major component of bile that induces this migration. We investigated the neuronal control of...