A case report involving suppressed nuclear receptor transcription factors 4a1 and Stevens-Johnson syndrome induced by a single dose of pembrolizumab and successfully treated with early steroid administration, resulting in complete remission of stage III lung cancer

• Main Authors: Maiko Machida (Author), Chika Yamazaki (Author), Nao Kouda (Author), Yousei Hanai (Author), Hideki Sato (Author), Ainari Konda (Author), Yuka Yamagata (Author), Tatsuya Itho (Author), Haruhiko Aisaka (Author)
• Format: Book
• Published: BMC, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Immunotherapy with immune checkpoint inhibitors is associated with immune-related adverse events (irAEs). A positive correlation between treatment efficacy and irAEs has been reported. Clinical indicators are required for appropriate interventions, such as steroid administration,...