Selective and rapid determination of raltegravir in human plasma by liquid chromatographyâtandem mass spectrometry in the negative ionization mode

• Asıl Yazarlar: Ajay Gupta (Yazar), Swati Guttikar (Yazar), Priyanka A. Shah (Yazar), Gajendra Solanki (Yazar), Pranav S. Shrivastav (Yazar), Mallika Sanyal (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2015-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

A selective and rapid high-performance liquid chromatographyâtandem mass spectrometry method was developed and validated for the quantification of raltegravir using raltegravir-d3 as an internal standard (IS). The analyte and IS were extracted with methylene chloride and n-hexane solvent mixture fro...