Ubp43 gene expression is required for normal Isg15 expression and fetal development

• Main Authors: Shen Meifeng (Author), Yan Ming (Author), Ritchie Kenneth J (Author), Austin Kathleen J (Author), Rempel Lea A (Author), Zhang Dong-Er (Author), Henkes Luiz E (Author), Hansen Thomas R (Author)
• Format: Book
• Published: BMC, 2007-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Isg15 covalently modifies murine endometrial proteins in response to early pregnancy. Isg15 can also be severed from targeted proteins by a specific protease called Ubp43 (Usp18). Mice lacking Ubp43 (null) form increased conjugated I...