Jagged-1 is induced by mTOR inhibitors in renal cancer cells through an Akt/ALK5/Smad4-dependent mechanism

The mammalian target of rapamycin (mTOR) plays an important role in the aggressiveness and therapeutic resistance of many cancers. Targeting mTOR continues to be under clinical investigation for cancer therapy. Despite the notable clinical success of mTOR inhibitors in extending the overall survival...

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Main Authors: David Danielpour (Author), Sarah Corum (Author), Patrick Leahy (Author), Anusha Bangalore (Author)
Format: Book
Published: Elsevier, 2022-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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