Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines

• Main Authors: Kirti S. Prabhu (Author), Kodappully Sivaraman Siveen (Author), Shilpa Kuttikrishnan (Author), Ahmad N. Iskandarani (Author), Abdul Q. Khan (Author), Maysaloun Merhi (Author), Halima E. Omri (Author), Said Dermime (Author), Tamam El-Elimat (Author), Nicholas H. Oberlies (Author), Feras Q. Alali (Author), Shahab Uddin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Therapeutic agents used in the treatment of cancer are known to develop resistance against cancer cells. Hence, there is a continuing need to investigate novel agents for the treatment and management of cancer. Antitumor activity of greensporone C (GC), a new resorcylic acid lactone isolated from an...