Preparation and optimization of microemulsion of rosuvastatin calcium

• Автори: B Zalak Patel (Автор), S Kruti Patel (Автор), S Ankit Shah (Автор), I Naazneen Surti (Автор)
• Формат: Книга
• Опубліковано: Wolters Kluwer Medknow Publications, 2012-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Due to very less bioavailability (20%) of Rosuvastatin calcium, an attempt was made to develop and optimize microemulsion formulation. Capmul MCM, Tween 20 and PEG 400 were selected as oil, surfactant and cosurfactant respectively as the drug is having higher solubility in them. 3:1% w/w S:CoS was s...