Stabilization of G protein-coupled receptors by point mutations

• Главные авторы: Franziska eHeydenreich (Автор), Ziva eVuckovic (Автор), Milos eMatkovic (Автор), Dmitry eVeprintsev (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2015-04-01T00:00:00Z.
• Предметы: article
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G protein-coupled receptors (GPCRs) are flexible integral membrane proteins involved in transmembrane signaling. Their involvement in many physiological processes makes them interesting targets for drug development. Determination of the structure of these receptors will help to design more specific...