Hypnozoite depletion in successive Plasmodium vivax relapses.

• Main Authors: Rintis Noviyanti (Author), Kelly Carey-Ewend (Author), Leily Trianty (Author), Christian Parobek (Author), Agatha Mia Puspitasari (Author), Sujata Balasubramanian (Author), Zackary Park (Author), Nicholas Hathaway (Author), Retno A S Utami (Author), Saraswati Soebianto (Author), Jeny Jeny (Author), Frilasita Yudhaputri (Author), Aditya Perkasa (Author), Farah N Coutrier (Author), Yusrifar K Tirta (Author), Lenny Ekawati (Author), Bagus Tjahyono (Author), Inge Sutanto (Author), Erni J Nelwan (Author), Herawati Sudoyo (Author), J Kevin Baird (Author), Jessica T Lin (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Genotyping Plasmodium vivax relapses can provide insights into hypnozoite biology. We performed targeted amplicon sequencing of 127 relapses occurring in Indonesian soldiers returning to malaria-free Java after yearlong deployment in malarious Eastern Indonesia. Hepatic carriage of multiple hypnozoi...