Origin of Circulating Free DNA in Sepsis: Analysis of the CLP Mouse Model

• Main Authors: Shigeto Hamaguchi (Author), Yukihiro Akeda (Author), Norihisa Yamamoto (Author), Masafumi Seki (Author), Kouji Yamamoto (Author), Kazunori Oishi (Author), Kazunori Tomono (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recently, it has been reported that circulating free DNA (cf-DNA) in the blood is increased in various infectious diseases, including sepsis. Moreover, a relationship between cf-DNA and neutrophil extracellular traps (NETs) has been suggested. However, it is still unclear what the source and physiol...