PGK1 facilities cisplatin chemoresistance by triggering HSP90/ERK pathway mediated DNA repair and methylation in endometrial endometrioid adenocarcinoma

• Asıl Yazarlar: Jing-Wei Zhou (Yazar), Juan-Juan Tang (Yazar), Wei Sun (Yazar), Hui Wang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2019-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Background Endometrial carcinoma represents one of the most common cancer types of the female reproductive tract. If diagnosed at an early stage, the 5-year survival rate is promising. However, recurrence and chemoresistance remain problematic for at least 15% of the patients. In the presen...