Cannabinoid Receptor 2 Signalling Bias Elicited by 2,4,6-Trisubstituted 1,3,5-Triazines

• Main Authors: Caitlin R. M. Oyagawa (Author), Sara M. de la Harpe (Author), Yurii Saroz (Author), Michelle Glass (Author), Andrea J. Vernall (Author), Natasha Lillia Grimsey (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2018-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Cannabinoid receptor 2 (CB2) is predominantly distributed in immune tissues and cells and is a promising therapeutic target for modulating inflammation. In this study we designed and synthesised a series of 2,4,6-trisubstituted 1,3,5-triazines with piperazinylalkyl or 1,2-diethoxyethane (PEG2) chain...