Cucurbitacin D exhibits its anti-cancer effect in human breast cancer cells by inhibiting Stat3 and Akt signaling

• Main Authors: Jin Mo Ku (Author), Se Hyang Hong (Author), Hyo In Kim (Author), Ye Seul Lim (Author), Sol Ji Lee (Author), Mia Kim (Author), Hye Sook Seo (Author), Yong Cheol Shin (Author), Seong-Gyu Ko (Author)
• Format: Book
• Published: SAGE Publishing, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cucurbitacins are triterpenoids commonly found in Cucurbitaceae and Cruciferae and have long been used in traditional medicine. Cucurbitacins demonstrate anti-inflammatory and anti-cancer activities. We investigated whether cucurbitacin D affects viability in breast cancer cells and its mechanism of...