Ferroptosis as an emerging therapeutic target in liver diseases

• Main Authors: Yuzhen Lu (Author), Junjie Hu (Author), Liang Chen (Author), Shan Li (Author), Ming Yuan (Author), Xianxiang Tian (Author), Peng Cao (Author), Zhenpeng Qiu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ferroptosis is an iron-dependently nonapoptotic cell death characterized by excessive accumulation of lipid peroxides and cellular iron metabolism disturbances. Impaired iron homeostasis and dysregulation of metabolic pathways are contributors to ferroptosis. As a major metabolic hub, the liver synt...